Cellular senescence due to telomere dysfunction has been hypothesized to play a role in age-associated diseases including SAW idiopathic pulmonary fibrosis (IPF).It has been postulated that paracrine mediators originating from senescent alveolar epithelia signal to surrounding mesenchymal cells and contribute to disease pathogenesis.However, murine
The Faraday laser, with Faraday anomalous dispersion optical filter (FADOF) as frequency-selection element, is a natural narrow-bandwidth light source for laser physic experiments.In this work, a dual-frequency (DF) Faraday laser is demonstrated for the first time on Cs D2 line at 852 nm.The frequencies of the two modes of DF Faraday laser hinge on
Broadly neutralizing antibodies are considered an important part of a successful HIV vaccine.A better understanding of the factors underlying their development during infection and of the epitopes they target is needed to elicit similar antibody responses by vaccination.We and others reported that, on average, it takes 2 to 3 years for cross-reacti